IBest to refer to the bathroom interior elevations. One area of danger is the wall thickness behind the wc. If they play to put wainscoting, tile or stone on the wall, the toilet stub better be more than 12-1/2" off rough wall.
illegal in Ky to bring thru floor,each fixture has to have individual ventI prefer bringing the drain up through the floor. AAVs are legal here. Only thing I need to be concerned with is drawers.